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Microhomology-mediated end joining: new players join the team

DNA double-strand breaks (DSBs) are the most deleterious type of DNA damage in cells arising from endogenous and exogenous attacks on the genomic DNA. Timely and properly repair of DSBs is important for genomic integrity and survival. MMEJ is an error-prone repair mechanism for DSBs, which relies on...

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Detalles Bibliográficos
Autores principales: Wang, Hailong, Xu, Xingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237343/
https://www.ncbi.nlm.nih.gov/pubmed/28101326
http://dx.doi.org/10.1186/s13578-017-0136-8