Upregulation of NOXA by 10-Hydroxycamptothecin plays a key role in inducing fibroblasts apoptosis and reducing epidural fibrosis

The fibrosis that develops following laminectomy or discectomy often causes serious complications, and the proliferation of fibroblasts is thought to be the major cause of epidural fibrosis. 10-Hydroxycamptothecin (HCPT) has been proven to be efficient in preventing epidural fibrosis, but the exact...

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Detalles Bibliográficos
Autores principales: Dai, Jihang, Sun, Yu, Yan, Lianqi, Wang, Jingcheng, Li, Xiaolei, He, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237371/
https://www.ncbi.nlm.nih.gov/pubmed/28097065
http://dx.doi.org/10.7717/peerj.2858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237371/
https://www.ncbi.nlm.nih.gov/pubmed/28097065
http://dx.doi.org/10.7717/peerj.2858

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