Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase

Neuronal degeneration in multiple sclerosis has been linked to oxidative stress. Dimethyl fumarate (DMF) is an effective oral therapeutic option shown to reduce disease activity and progression in patients with relapsing-remitting multiple sclerosis. DMF activates the transcription factor nuclear fa...

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Detalles Bibliográficos
Autores principales: Hoffmann, Christina, Dietrich, Michael, Herrmann, Ann-Kathrin, Schacht, Teresa, Albrecht, Philipp, Methner, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237454/
https://www.ncbi.nlm.nih.gov/pubmed/28116039
http://dx.doi.org/10.1155/2017/6093903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237454/
https://www.ncbi.nlm.nih.gov/pubmed/28116039
http://dx.doi.org/10.1155/2017/6093903

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