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Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase
Neuronal degeneration in multiple sclerosis has been linked to oxidative stress. Dimethyl fumarate (DMF) is an effective oral therapeutic option shown to reduce disease activity and progression in patients with relapsing-remitting multiple sclerosis. DMF activates the transcription factor nuclear fa...
Autores principales: | Hoffmann, Christina, Dietrich, Michael, Herrmann, Ann-Kathrin, Schacht, Teresa, Albrecht, Philipp, Methner, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237454/ https://www.ncbi.nlm.nih.gov/pubmed/28116039 http://dx.doi.org/10.1155/2017/6093903 |
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