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Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling Pathway

Uric acid (UA) is a risk factor for endothelial dysfunction, a process in which inflammation may play an important role. UA increases high mobility group box chromosomal protein 1 (HMGB1) expression and extracellular release in endothelial cells. HMGB1 is an inflammatory cytokine that interacts with...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Duan, Xi-Mei, Liu, Ying, Yu, Jiao, Tang, Yun-Liang, Liu, Ze-Lin, Jiang, Shan, Zhang, Chun-Ping, Liu, Jian-Ying, Xu, Ji-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237466/
https://www.ncbi.nlm.nih.gov/pubmed/28116308
http://dx.doi.org/10.1155/2017/4391920