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Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling Pathway
Uric acid (UA) is a risk factor for endothelial dysfunction, a process in which inflammation may play an important role. UA increases high mobility group box chromosomal protein 1 (HMGB1) expression and extracellular release in endothelial cells. HMGB1 is an inflammatory cytokine that interacts with...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237466/ https://www.ncbi.nlm.nih.gov/pubmed/28116308 http://dx.doi.org/10.1155/2017/4391920 |