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Optimizing k-mer size using a variant grid search to enhance de novo genome assembly
Largely driven by huge reductions in per-base costs, sequencing nucleic acids has become a near-ubiquitous technique in laboratories performing biological and biomedical research. Most of the effort goes to re-sequencing, but assembly of de novogenerated, raw sequence reads into contigs that span as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Biomedical Informatics
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237644/ https://www.ncbi.nlm.nih.gov/pubmed/28104957 http://dx.doi.org/10.6026/97320630012036 |