VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors

The inadequate transport of drugs into the tumor tissue caused by its abnormal vasculature is a major obstacle to the treatment of cancer. Anti-vascular endothelial growth factor (anti-VEGF) drugs can cause phenotypic alteration and maturation of the tumor's vasculature. However, whether this c...

Descripción completa

Detalles Bibliográficos
Autores principales: Röhrig, F, Vorlová, S, Hoffmann, H, Wartenberg, M, Escorcia, F E, Keller, S, Tenspolde, M, Weigand, I, Gätzner, S, Manova, K, Penack, O, Scheinberg, D A, Rosenwald, A, Ergün, S, Granot, Z, Henke, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237662/
https://www.ncbi.nlm.nih.gov/pubmed/27270432
http://dx.doi.org/10.1038/onc.2016.182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237662/
https://www.ncbi.nlm.nih.gov/pubmed/27270432
http://dx.doi.org/10.1038/onc.2016.182

Ejemplares similares