C0818, a novel curcumin derivative, interacts with Hsp90 and inhibits Hsp90 ATPase activity

The aims of the present study were to estimate the affinity between 3,5-(E)-bis(3-methoxy-4-hydroxybenzal)-4-piperidinone hydrochloride (C0818) and heat shock protein 90 (Hsp90) and to investigate the inhibitory effects of this compound on Hsp90 ATPase activity. Fluorescence spectroscopy was used to...

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Detalles Bibliográficos
Autores principales: Fan, Yingjuan, Liu, Yang, Zhang, Lianru, Cai, Fang, Zhu, Liping, Xu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237709/
https://www.ncbi.nlm.nih.gov/pubmed/28119813
http://dx.doi.org/10.1016/j.apsb.2016.05.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237709/
https://www.ncbi.nlm.nih.gov/pubmed/28119813
http://dx.doi.org/10.1016/j.apsb.2016.05.014

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