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C0818, a novel curcumin derivative, interacts with Hsp90 and inhibits Hsp90 ATPase activity
The aims of the present study were to estimate the affinity between 3,5-(E)-bis(3-methoxy-4-hydroxybenzal)-4-piperidinone hydrochloride (C0818) and heat shock protein 90 (Hsp90) and to investigate the inhibitory effects of this compound on Hsp90 ATPase activity. Fluorescence spectroscopy was used to...
Autores principales: | Fan, Yingjuan, Liu, Yang, Zhang, Lianru, Cai, Fang, Zhu, Liping, Xu, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237709/ https://www.ncbi.nlm.nih.gov/pubmed/28119813 http://dx.doi.org/10.1016/j.apsb.2016.05.014 |
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