Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo

Tubulin has been shown to be an effective target for the development of cytotoxic agents against prostate cancer. Previously, we reported that Lx2-32c is an anti-tubulin agent with high binding affinity to tubulin. In this study, we investigated the potential of Lx2-32c to act as an effective cytoto...

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Detalles Bibliográficos
Autores principales: Lv, Guangyao, Sun, Dengjun, Zhang, Jingwen, Xie, Xiaoxia, Wu, Xiaoqiong, Fang, Weishuo, Tian, Jingwei, Yan, Chunhong, Wang, Hongbo, Fu, Fenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237719/
https://www.ncbi.nlm.nih.gov/pubmed/28119808
http://dx.doi.org/10.1016/j.apsb.2016.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237719/
https://www.ncbi.nlm.nih.gov/pubmed/28119808
http://dx.doi.org/10.1016/j.apsb.2016.06.005

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