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Osteopontin regulates macrophage activation and osteoclast formation in hypertensive patients with vascular calcification

Vascular calcification (VC) is a highly regulated ectopic mineral deposition process involving immune cell infiltration in the vasculatures, which has been recognized to be promoted by hypertension. The matricellular glycoprotein osteopontin (OPN) is strongly induced in myeloid cells as a potential...

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Detalles Bibliográficos
Autores principales: Ge, Qian, Ruan, Cheng-Chao, Ma, Yu, Tang, Xiao-Feng, Wu, Qi-Hong, Wang, Ji-Guang, Zhu, Ding-Liang, Gao, Ping-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238370/
https://www.ncbi.nlm.nih.gov/pubmed/28091516
http://dx.doi.org/10.1038/srep40253