Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type

In most human sporadic prion diseases the phenotype is consistently associated with specific pairings of the genotype at codon 129 of the prion protein gene and conformational properties of the scrapie PrP (PrP(Sc)) grossly identified types 1 and 2. This association suggests that the 129 genotype fa...

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Detalles Bibliográficos
Autores principales: Cracco, Laura, Notari, Silvio, Cali, Ignazio, Sy, Man-Sun, Chen, Shu G., Cohen, Mark L., Ghetti, Bernardino, Appleby, Brian S., Zou, Wen-Quan, Caughey, Byron, Safar, Jiri G., Gambetti, Pierluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238384/
https://www.ncbi.nlm.nih.gov/pubmed/28091514
http://dx.doi.org/10.1038/srep38280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238384/
https://www.ncbi.nlm.nih.gov/pubmed/28091514
http://dx.doi.org/10.1038/srep38280

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