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A disrupted transsulphuration pathway results in accumulation of redox metabolites and induction of gametocytogenesis in malaria
Intra-erythrocytic growth of malaria parasite is known to induce redox stress. In addition to haem degradation which generates reactive oxygen species (ROS), the parasite is also thought to efflux redox active homocysteine. To understand the basis underlying accumulation of homocysteine, we have exa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238400/ https://www.ncbi.nlm.nih.gov/pubmed/28091526 http://dx.doi.org/10.1038/srep40213 |