Apelin receptor homodimer-oligomers revealed by single-molecule imaging and novel G protein-dependent signaling

The apelin receptor (APJ) belongs to family A of the G protein-coupled receptors (GPCRs) and is a potential pharmacotherapeutic target for heart failure, hypertension, and other cardiovascular diseases. There is evidence APJ heterodimerizes with other GPCRs; however, the existence of APJ homodimers...

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Detalles Bibliográficos
Autores principales: Cai, Xin, Bai, Bo, Zhang, Rumin, Wang, Chunmei, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238433/
https://www.ncbi.nlm.nih.gov/pubmed/28091541
http://dx.doi.org/10.1038/srep40335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238433/
https://www.ncbi.nlm.nih.gov/pubmed/28091541
http://dx.doi.org/10.1038/srep40335

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