pH, Lactate, and Hypoxia: Reciprocity in Regulating High-Affinity Monocarboxylate Transporter Expression in Glioblastoma()

Highly malignant brain tumors harbor the aberrant propensity for aerobic glycolysis, the excessive conversion of glucose to lactic acid even in the presence of ample tissue oxygen. Lactic acid is rapidly effluxed to the tumor microenvironment via a group of plasma-membrane transporters denoted monoc...

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Detalles Bibliográficos
Autores principales: Caruso, James P., Koch, Brandon J., Benson, Philip D., Varughese, Elsa, Monterey, Michael D., Lee, Amy E., Dave, Ajal M., Kiousis, Sam, Sloan, Andrew E., Mathupala, Saroj P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238458/
https://www.ncbi.nlm.nih.gov/pubmed/28092823
http://dx.doi.org/10.1016/j.neo.2016.12.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238458/
https://www.ncbi.nlm.nih.gov/pubmed/28092823
http://dx.doi.org/10.1016/j.neo.2016.12.011

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