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1,2,4-Triazolidine-3-thiones as Narrow Spectrum Antibiotics against Multidrug-Resistant Acinetobacter baumannii

[Image: see text] With only two new classes of antibiotics developed in the last 40 years, novel antibiotics are desperately needed to combat the growing problem of multidrug-resistant and extensively drug resistant bacteria, particularly Gram-negative bacteria. Described in this letter is the synth...

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Detalles Bibliográficos
Autores principales: Huggins, William M., Minrovic, Bradley M., Corey, Brendan W., Jacobs, Anna C., Melander, Roberta J., Sommer, Roger D., Zurawski, Daniel V., Melander, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238477/
https://www.ncbi.nlm.nih.gov/pubmed/28105270
http://dx.doi.org/10.1021/acsmedchemlett.6b00296