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A population-based statistical approach identifies parameters characteristic of human microRNA-mRNA interactions

BACKGROUND: MicroRNAs are ~17–24 nt. noncoding RNAs found in all eukaryotes that degrade messenger RNAs via RNA interference (if they bind in a perfect or near-perfect complementarity to the target mRNA), or arrest translation (if the binding is imperfect). Several microRNA targets have been identif...

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Detalles Bibliográficos
Autores principales: Smalheiser, Neil R, Torvik, Vetle I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC523849/
https://www.ncbi.nlm.nih.gov/pubmed/15453917
http://dx.doi.org/10.1186/1471-2105-5-139