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High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy

Evidence indicates that hyaluronic acid (HA) mitigates tendinopathy, but the effect of molecular weight is unclear. We investigated the effects of different concentrations and different molecular weights of HA (350 kDa, 1500 kDa, and 3000 kDa) on matrix metalloproteinase (MMP)-1 and -3 expression in...

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Detalles Bibliográficos
Autores principales: Wu, Po-Ting, Kuo, Li-Chieh, Su, Fong-Chin, Chen, Shih-Yao, Hsu, Tai-I, Li, Chung-Yi, Tsai, Kuen-Jer, Jou, I-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238506/
https://www.ncbi.nlm.nih.gov/pubmed/28091588
http://dx.doi.org/10.1038/srep40840