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Synthesis, dynamic NMR characterization and XRD studies of novel N,N’-substituted piperazines for bioorthogonal labeling

Novel, functionalized piperazine derivatives were successfully synthesized and fully characterized by (1)H/(13)C/(19)F NMR, MS, elemental analysis and lipophilicity. All piperazine compounds occur as conformers resulting from the partial amide double bond. Furthermore, a second conformational shape...

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Detalles Bibliográficos
Autores principales: Mamat, Constantin, Pretze, Marc, Gott, Matthew, Köckerling, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238536/
https://www.ncbi.nlm.nih.gov/pubmed/28144316
http://dx.doi.org/10.3762/bjoc.12.242