Facile synthesis of a 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis

Access to 3-deazaadenosine (c(3)A) building blocks for RNA solid-phase synthesis represents a severe bottleneck in modern RNA research, in particular for atomic mutagenesis experiments to explore mechanistic aspects of ribozyme catalysis. Here, we report the 5-step synthesis of a c(3)A phosphoramidi...

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Detalles Bibliográficos
Autores principales: Mairhofer, Elisabeth, Fuchs, Elisabeth, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238537/
https://www.ncbi.nlm.nih.gov/pubmed/28144324
http://dx.doi.org/10.3762/bjoc.12.250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238537/
https://www.ncbi.nlm.nih.gov/pubmed/28144324
http://dx.doi.org/10.3762/bjoc.12.250

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