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Synthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactions

Herein we describe a versatile approach for the synthesis of acylhydrazino-peptomers, a new class of peptidomimetics. The key idea in this approach is based on a simple route using a one-pot hydrazino-Ugi four-component reaction followed by a hydrazinolysis or hydrolysis reaction and subsequent hydr...

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Detalles Bibliográficos
Autores principales: Barreto, Angélica de Fátima S, dos Santos, Veronica Alves, Andrade, Carlos Kleber Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238544/
https://www.ncbi.nlm.nih.gov/pubmed/28144359
http://dx.doi.org/10.3762/bjoc.12.285