Copper-catalyzed asymmetric sp(3) C–H arylation of tetrahydroisoquinoline mediated by a visible light photoredox catalyst

This report describes a highly enantioselective oxidative sp(3) C–H arylation of N-aryltetrahydroisoquinolines (THIQs) through a dual catalysis platform. The combination of the photoredox catalyst, [Ir(ppy)(2)(dtbbpy)]PF(6), and chiral copper catalysts provide a mild and highly effective sp(3) C–H a...

Descripción completa

Detalles Bibliográficos
Autores principales: Querard, Pierre, Perepichka, Inna, Zysman-Colman, Eli, Li, Chao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238558/
https://www.ncbi.nlm.nih.gov/pubmed/28144334
http://dx.doi.org/10.3762/bjoc.12.260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238558/
https://www.ncbi.nlm.nih.gov/pubmed/28144334
http://dx.doi.org/10.3762/bjoc.12.260

Ejemplares similares