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Copper-catalyzed asymmetric sp(3) C–H arylation of tetrahydroisoquinoline mediated by a visible light photoredox catalyst
This report describes a highly enantioselective oxidative sp(3) C–H arylation of N-aryltetrahydroisoquinolines (THIQs) through a dual catalysis platform. The combination of the photoredox catalyst, [Ir(ppy)(2)(dtbbpy)]PF(6), and chiral copper catalysts provide a mild and highly effective sp(3) C–H a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238558/ https://www.ncbi.nlm.nih.gov/pubmed/28144334 http://dx.doi.org/10.3762/bjoc.12.260 |