Topoisomerase I inhibition leads to length-dependent gene expression changes in human primary astrocytes

Topoisomerase I is required for the proper expression of long genes (> 100 kb) in mouse and human cortical neurons, including many candidate genes for autism spectrum disorder (ASD) [1]. Given the important role of astrocytes in brain development [2], we investigated whether long genes, including...

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Detalles Bibliográficos
Autores principales: Gokoolparsadh, Akira, Fang, Zhiming, Braidy, Nady, Voineagu, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238604/
https://www.ncbi.nlm.nih.gov/pubmed/28119819
http://dx.doi.org/10.1016/j.gdata.2016.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238604/
https://www.ncbi.nlm.nih.gov/pubmed/28119819
http://dx.doi.org/10.1016/j.gdata.2016.12.005

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