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Thiazol-4-one derivatives from the reaction of monosubstituted thioureas with maleimides: structures and factors determining the selectivity and tautomeric equilibrium in solution

2-(Alkyl(aryl)amino)thiazol-4(5H)-ones can regioselectively be prepared from monoalkyl(aryl)thioureas and maleimides. In solution, the former heterocycles exist in a tautomeric equilibrium with 2-(alkyl(aryl)imino)thiazolidin-4-ones and the substituent on the exocyclic nitrogen atom governs the rati...

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Detalles Bibliográficos
Autores principales: Pankova, Alena S, Golubev, Pavel R, Khlebnikov, Alexander F, Ivanov, Alexander Yu, Kuznetsov, Mikhail A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238611/
https://www.ncbi.nlm.nih.gov/pubmed/28144325
http://dx.doi.org/10.3762/bjoc.12.251