Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases

The trans-2-deoxyribosylation of 4-thiouracil ((4S)Ura) and 2-thiouracil ((2S)Ura), as well as 6-azauracil, 6-azathymine and 6-aza-2-thiothymine was studied using dG and E. coli purine nucleoside phosphorylase (PNP) for the in situ generation of 2-deoxy-α-D-ribofuranose-1-phosphate (dRib-1P) followe...

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Detalles Bibliográficos
Autores principales: Stepchenko, Vladimir A, Miroshnikov, Anatoly I, Seela, Frank, Mikhailopulo, Igor A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238616/
https://www.ncbi.nlm.nih.gov/pubmed/28144328
http://dx.doi.org/10.3762/bjoc.12.254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238616/
https://www.ncbi.nlm.nih.gov/pubmed/28144328
http://dx.doi.org/10.3762/bjoc.12.254

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