Thioredoxin-dependent disulfide bond reduction is required for protamine eviction from sperm chromatin

Cysteine oxidation in protamines leads to their oligomerization and contributes to sperm chromatin compaction. Here we identify the Drosophila thioredoxin Deadhead (DHD) as the factor responsible for the reduction of intermolecular disulfide bonds in protamines and their eviction from sperm during f...

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Detalles Bibliográficos
Autores principales: Emelyanov, Alexander V., Fyodorov, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238724/
https://www.ncbi.nlm.nih.gov/pubmed/28031247
http://dx.doi.org/10.1101/gad.290916.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238724/
https://www.ncbi.nlm.nih.gov/pubmed/28031247
http://dx.doi.org/10.1101/gad.290916.116

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