CTCF-mediated topological boundaries during development foster appropriate gene regulation

The genome is organized into repeating topologically associated domains (TADs), each of which is spatially isolated from its neighbor by poorly understood boundary elements thought to be conserved across cell types. Here, we show that deletion of CTCF (CCCTC-binding factor)-binding sites at TAD and...

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Detalles Bibliográficos
Autores principales: Narendra, Varun, Bulajić, Milica, Dekker, Job, Mazzoni, Esteban O., Reinberg, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238725/
https://www.ncbi.nlm.nih.gov/pubmed/28087711
http://dx.doi.org/10.1101/gad.288324.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238725/
https://www.ncbi.nlm.nih.gov/pubmed/28087711
http://dx.doi.org/10.1101/gad.288324.116

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