Protein splicing of a recombinase intein induced by ssDNA and DNA damage

Inteins (or protein introns) autocatalytically excise themselves through protein splicing. We challenge the long-considered notion that inteins are merely molecular parasites and posit that some inteins evolved to regulate host protein function. Here we show substrate-induced and DNA damage-induced...

Descripción completa

Detalles Bibliográficos
Autores principales: Lennon, Christopher W., Stanger, Matthew, Belfort, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238726/
https://www.ncbi.nlm.nih.gov/pubmed/28031248
http://dx.doi.org/10.1101/gad.289280.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238726/
https://www.ncbi.nlm.nih.gov/pubmed/28031248
http://dx.doi.org/10.1101/gad.289280.116

Ejemplares similares