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Comparison of SHAPE reagents for mapping RNA structures inside living cells
Recent advances in SHAPE technology have converted the classic primer extension method to next-generation sequencing platforms, allowing transcriptome-level analysis of RNA secondary structure. In particular, icSHAPE and SHAPE-MaP, using NAI-N(3) and 1M7 reagents, respectively, are methods that clai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238792/ https://www.ncbi.nlm.nih.gov/pubmed/27879433 http://dx.doi.org/10.1261/rna.058784.116 |