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Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

Cell biology differs between traditional cell culture and 3-dimensional (3-D) systems, and is modulated by the extracellular matrix. Experimentation in 3-D presents challenges, especially with virulent pathogens. Mycobacterium tuberculosis (Mtb) kills more humans than any other infection and is char...

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Detalles Bibliográficos
Autores principales: Tezera, Liku B, Bielecka, Magdalena K, Chancellor, Andrew, Reichmann, Michaela T, Shammari, Basim Al, Brace, Patience, Batty, Alex, Tocheva, Annie, Jogai, Sanjay, Marshall, Ben G, Tebruegge, Marc, Jayasinghe, Suwan N, Mansour, Salah, Elkington, Paul T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238961/
https://www.ncbi.nlm.nih.gov/pubmed/28063256
http://dx.doi.org/10.7554/eLife.21283