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PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity!

Progesterone receptor membrane component 1 (PGRMC1) is a multifunctional protein implicated in multiple pathologies, including cancer and Alzheimer's disease. The recently published structure of PGRMC1 revealed heme-mediated dimerization that directed the PGRMC1-dependent cytochrome P450-mediat...

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Detalles Bibliográficos
Autores principales: Cahill, Michael A., Jazayeri, Jalal A., Kovacevic, Zaklina, Richardson, Des R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239438/
https://www.ncbi.nlm.nih.gov/pubmed/27448967
http://dx.doi.org/10.18632/oncotarget.10691