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Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte

Epsins are a conserved family of endocytic adaptors essential for diverse biological events. However, its role in oocytes remains completely unknown. Here, we report that specific depletion of Epsin2 in mouse oocytes significantly disrupts meiotic progression. Confocal microscopy reveals that Epsin2...

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Detalles Bibliográficos
Autores principales: Li, Ling, Han, Longsen, Zhang, Jiaqi, Liu, Xiaohui, Ma, Rujun, Hou, Xiaojing, Ge, Juan, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239448/
https://www.ncbi.nlm.nih.gov/pubmed/27463009
http://dx.doi.org/10.18632/oncotarget.10815