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Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte
Epsins are a conserved family of endocytic adaptors essential for diverse biological events. However, its role in oocytes remains completely unknown. Here, we report that specific depletion of Epsin2 in mouse oocytes significantly disrupts meiotic progression. Confocal microscopy reveals that Epsin2...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239448/ https://www.ncbi.nlm.nih.gov/pubmed/27463009 http://dx.doi.org/10.18632/oncotarget.10815 |