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The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

The HIPPO pathway is an evolutionary conserved regulator of organ size that controls both cell proliferation and death. This pathway has an important role in mediating cell death in response to oxidative stress through the inactivation of Yes-associated protein (YAP) and inhibition of anti-oxidant g...

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Detalles Bibliográficos
Autores principales: Rajesh, Kamindla, Krishnamoorthy, Jothilatha, Gupta, Jyotsana, Kazimierczak, Urszula, Papadakis, Andreas I., Deng, Zhilin, Wang, Shuo, Kuninaka, Shinji, Koromilas, Antonis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239457/
https://www.ncbi.nlm.nih.gov/pubmed/27409837
http://dx.doi.org/10.18632/oncotarget.10480