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RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy
Originally identified as an E3 ligase regulating toll-like receptor (TLR) signaling, ring finger protein 216 (RNF216) also plays an essential role in autophagy, which is fundamental to cellular homeostasis. Autophagy dysfunction leads to an array of pathological events, including tumor formation. In...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239467/ https://www.ncbi.nlm.nih.gov/pubmed/27203674 http://dx.doi.org/10.18632/oncotarget.9433 |