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RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy

Originally identified as an E3 ligase regulating toll-like receptor (TLR) signaling, ring finger protein 216 (RNF216) also plays an essential role in autophagy, which is fundamental to cellular homeostasis. Autophagy dysfunction leads to an array of pathological events, including tumor formation. In...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Yanan, Qian, Liu, Wang, Xue, Gu, Hailiang, Dong, Xiaoqiang, Huang, Shiqian, Jin, Min, Ge, Hailiang, Xu, Congfeng, Zhang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239467/
https://www.ncbi.nlm.nih.gov/pubmed/27203674
http://dx.doi.org/10.18632/oncotarget.9433