Icaritin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling

Icaritin (IT) is a flavonoid isolated from Herba Epimedii. In this study, we evaluated the anti-melanoma activities of IT, and determined its cytotoxic mechanism. We found that IT exerted cytotoxicity to melanoma cells. Furthermore, IT induced melanoma cell apoptosis, which was accompanied with PARP...

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Detalles Bibliográficos
Autores principales: Wu, Jinfeng, Du, Juan, Fu, Xiuqiong, Liu, Bin, Cao, Huihui, Li, Ting, Su, Tao, Xu, Jinhua, Tse, Anfernee Kai-Wing, Yu, Zhi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239473/
https://www.ncbi.nlm.nih.gov/pubmed/27323414
http://dx.doi.org/10.18632/oncotarget.9984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239473/
https://www.ncbi.nlm.nih.gov/pubmed/27323414
http://dx.doi.org/10.18632/oncotarget.9984

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