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Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Little information is available about the role of certain mutations for clonal evolution and the clinical outcome during relapse in diffuse large B-cell lymphoma (DLBCL). Therefore, we analyzed formalin-fixed-paraffin-embedded tumor samples from first diagnosis, relapsed or refractory disease from 2...

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Detalles Bibliográficos
Autores principales: Melchardt, Thomas, Hufnagl, Clemens, Weinstock, David M., Kopp, Nadja, Neureiter, Daniel, Tränkenschuh, Wolfgang, Hackl, Hubert, Weiss, Lukas, Rinnerthaler, Gabriel, Hartmann, Tanja N., Greil, Richard, Weigert, Oliver, Egle, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239491/
https://www.ncbi.nlm.nih.gov/pubmed/27285986
http://dx.doi.org/10.18632/oncotarget.9860