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Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis

PURPOSE: To establish penile cancer (PeCa) cell lines for the study of molecular mechanisms of carcinogenesis and testing therapeutic reagents. MATERIALS AND METHODS: We successfully established two PeCa cell lines from fresh tumor tissues from 21 cases. One cell line named Penl1 was isolated from a...

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Detalles Bibliográficos
Autores principales: Chen, Jieping, Yao, Kai, Li, Zaishang, Deng, Chuangzhong, Wang, Liangjiao, Yu, Xingsu, Liang, Peili, Xie, Qiankun, Chen, Peng, Qin, Zike, Ye, Yunlin, Liu, Zhuowei, Zhou, Fangjian, Zhang, Zhenfeng, Han, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239507/
https://www.ncbi.nlm.nih.gov/pubmed/27351128
http://dx.doi.org/10.18632/oncotarget.10098