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ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma

Renal cell carcinoma (RCC) is the major cause of kidney malignancy-related deaths. Rho GTPases are key regulators in cancer cell metastasis. ARHGAP24, a Rac-specific member of the Rho GTPase-activating protein family, acts as a functional target of cancer cell migration and invasion. In the present...

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Detalles Bibliográficos
Autores principales: Xu, Gaosi, Lu, Xiongbing, Huang, Tianlun, Fan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239517/
https://www.ncbi.nlm.nih.gov/pubmed/27385097
http://dx.doi.org/10.18632/oncotarget.10386