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The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma

Chloramphenicol is an old antibiotic that also inhibits mammalian mitochondrial protein synthesis. Our studies demonstrated that chloramphenicol is highly cytotoxic to myeloma cells, acting in a dose- and time-dependent manner. Chloramphenicol sharply suppressed ATP levels in myeloma cells at concen...

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Detalles Bibliográficos
Autores principales: Tian, Faqing, Wang, Chunyan, Tang, Meiqin, Li, Juheng, Cheng, Xiaohui, Zhang, Sihan, Ji, Delan, Huang, Yingcai, Li, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239525/
https://www.ncbi.nlm.nih.gov/pubmed/27437770
http://dx.doi.org/10.18632/oncotarget.10623