Cargando…
The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma
Chloramphenicol is an old antibiotic that also inhibits mammalian mitochondrial protein synthesis. Our studies demonstrated that chloramphenicol is highly cytotoxic to myeloma cells, acting in a dose- and time-dependent manner. Chloramphenicol sharply suppressed ATP levels in myeloma cells at concen...
Autores principales: | Tian, Faqing, Wang, Chunyan, Tang, Meiqin, Li, Juheng, Cheng, Xiaohui, Zhang, Sihan, Ji, Delan, Huang, Yingcai, Li, Huiqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239525/ https://www.ncbi.nlm.nih.gov/pubmed/27437770 http://dx.doi.org/10.18632/oncotarget.10623 |
Ejemplares similares
-
MicroRNA-497 inhibits multiple myeloma growth and increases susceptibility to bortezomib by targeting Bcl-2
por: Tian, Faqing, et al.
Publicado: (2019) -
Microbial antigens-loaded myeloma cells enhance Th2 cell proliferation and myeloma clonogenicity via Th2–myeloma cell interaction
por: Tian, Faqing, et al.
Publicado: (2019) -
Structural, biological and pharmaceutical importance of antibiotic agent chloramphenicol
por: Sathya, A., et al.
Publicado: (2020) -
Unusual acylation of chloramphenicol in Lysobacter enzymogenes, a biocontrol agent with intrinsic resistance to multiple antibiotics
por: Zhang, Wei, et al.
Publicado: (2017) -
THE CLINICAL APPLICATION OF ANTIBIOTICS—CHLORAMPHENICOL AND THE TETRACYCLINES
Publicado: (1957)