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Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

Radiation therapy is a major primary treatment option for both localized early stage prostate cancer, and for advanced, regionally un-resectable, cancer. However, around 30% of patients still experience biochemical recurrence after radiation therapy within 10 years. Thus, identification of better bi...

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Detalles Bibliográficos
Autores principales: Rane, Jayant K., Erb, Holger H.H., Nappo, Giovanna, Mann, Vincent M., Simms, Matthew S., Collins, Anne T., Visakorpi, Tapio, Maitland, Norman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239528/
https://www.ncbi.nlm.nih.gov/pubmed/27340920
http://dx.doi.org/10.18632/oncotarget.10207