Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study

Oncogenic K-ras is capable to control tumor growth and progression by rewiring cancer metabolism. In vitro NIH-Ras cells convert glucose to lactate and use glutamine to sustain anabolic processes, but their in vivo environmental adaptation and multiple metabolic pathways activation ability is poorly...

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Detalles Bibliográficos
Autores principales: Gaglio, Daniela, Valtorta, Silvia, Ripamonti, Marilena, Bonanomi, Marcella, Damiani, Chiara, Todde, Sergio, Negri, Alfredo Simone, Sanvito, Francesca, Mastroianni, Fabrizia, Campli, Antonella Di, Turacchio, Gabriele, Di Grigoli, Giuseppe, Belloli, Sara, Luini, Alberto, Gilardi, Maria Carla, Colangelo, Anna Maria, Alberghina, Lilia, Moresco, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239532/
https://www.ncbi.nlm.nih.gov/pubmed/27409831
http://dx.doi.org/10.18632/oncotarget.10470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239532/
https://www.ncbi.nlm.nih.gov/pubmed/27409831
http://dx.doi.org/10.18632/oncotarget.10470

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