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Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization

The cAMP-responsive element-binding protein (CREB) is involved in the tumorigenicity of HER-2/neu-overexpressing murine and human tumor cells, but a link between the HER-2/neu-mediated CREB activation, its posttranslational modification and localization and changes in the cellular metabolism, due to...

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Detalles Bibliográficos
Autores principales: Steven, André, Leisz, Sandra, Sychra, Katharina, Hiebl, Bernhard, Wickenhauser, Claudia, Mougiakakos, Dimitrios, Kiessling, Rolf, Denkert, Carsten, Seliger, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239535/
https://www.ncbi.nlm.nih.gov/pubmed/27409833
http://dx.doi.org/10.18632/oncotarget.10474