Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

Actively proliferating Lgr5+ skin stem cells are found deep in the hair follicle (HF). These cells renew the HF and drive its expansion in anagen phase. Their long residence and continuous mitotic activity make them prime candidates to transform into skin tumor-initiating cells. This was investigate...

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Detalles Bibliográficos
Autores principales: van de Glind, Gerline C., Out, Jacoba J., Rebel, Heggert G., Tensen, Cornelis P., de Gruijl, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239536/
https://www.ncbi.nlm.nih.gov/pubmed/27409834
http://dx.doi.org/10.18632/oncotarget.10475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239536/
https://www.ncbi.nlm.nih.gov/pubmed/27409834
http://dx.doi.org/10.18632/oncotarget.10475

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