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MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5

OBJECTIVE: In this study, we aim to find out the role of microRNA-93-5p (miR-93) and Smad5 in morphine tolerance in mouse models of bone cancer pain (BCP). RESULTS: At 7 days after injection of morphine, the PMWT showed no significant difference between the morphine model group and the saline model...

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Detalles Bibliográficos
Autores principales: Xiao, Wen-Feng, Li, Yu-Sheng, Lou, Wei, Cai, Ting, Zhang, Shun, Hu, Xiao-Ying, Zhang, Xing-Wang, Luo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239538/
https://www.ncbi.nlm.nih.gov/pubmed/27438143
http://dx.doi.org/10.18632/oncotarget.10524