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Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer

Growth hormone-releasing hormone (GHRH) and its receptors have been implicated in the progression of various tumors. In vitro and in vivo studies have demonstrated that GHRH antagonists inhibit the growth of several cancers. GHRH antagonists, JMR-132 and JV-1-38 inhibit the growth of androgen-indepe...

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Detalles Bibliográficos
Autores principales: Muñoz-Moreno, Laura, Arenas, Maria Isabel, Carmena, María J., Schally, Andrew V., Sánchez-Chapado, Manuel, Prieto, Juan C., Bajo, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239544/
https://www.ncbi.nlm.nih.gov/pubmed/27448980
http://dx.doi.org/10.18632/oncotarget.10710