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A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy

Interleukin-15 has been implicated as a promising cytokine for cancer immunotherapy, while folate receptor α (FRα) has been shown to be a potentially useful target for colon cancer therapy. Herein, we developed F-PLP/pIL15, a FRα-targeted lipoplex loading recombinant interleukin-15 plasmid (pIL15) a...

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Detalles Bibliográficos
Autores principales: Liang, Xiao, Luo, Min, Wei, Xia-Wei, Ma, Cui-Cui, Yang, Yu-Han, Shao, Bin, Liu, Yan-Tong, Liu, Ting, Ren, Jun, Liu, Li, He, Zhi-Yao, Wei, Yu-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239545/
https://www.ncbi.nlm.nih.gov/pubmed/27438147
http://dx.doi.org/10.18632/oncotarget.10537