Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide

Peptide drug conjugates offer a novel strategy to achieve controlled drug release. This approach avoids the clinical obstacles of non-specific toxicity and overall drug resistance of conventional cytotoxic agents, such as paclitaxel. MMP2 plays important functions in tumour proliferation and metasta...

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Detalles Bibliográficos
Autores principales: Huang, Changjiang, Yi, Xiulin, Kong, Dexin, Chen, Ligong, Min, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239547/
https://www.ncbi.nlm.nih.gov/pubmed/27447567
http://dx.doi.org/10.18632/oncotarget.10735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239547/
https://www.ncbi.nlm.nih.gov/pubmed/27447567
http://dx.doi.org/10.18632/oncotarget.10735

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