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Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide
Peptide drug conjugates offer a novel strategy to achieve controlled drug release. This approach avoids the clinical obstacles of non-specific toxicity and overall drug resistance of conventional cytotoxic agents, such as paclitaxel. MMP2 plays important functions in tumour proliferation and metasta...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239547/ https://www.ncbi.nlm.nih.gov/pubmed/27447567 http://dx.doi.org/10.18632/oncotarget.10735 |